BCRP-IN-2 is a compound with BCRP inhibitory activity, exhibiting enhanced inhibition of BCRP upon UV activation. It serves as a valuable probe for studying interactions between quinazoline amine derivatives and BCRP, and it stimulates ATP hydrolysis of the BCRP transporter, leading to increased mitoxantrone accumulation in BCRP-overexpressing H460/MX20 cells.
Molekulargewicht:
339.35
CAS Nummer:
[2953730-35-1]
Formel:
C19H13N7
Target-Kategorie:
BCRP
T203499
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