Tubulin polymerization-IN-71 (Compound 4k) is an inhibitor of tubulin polymerization with an IC50 of 3.06 µM. It suppresses the proliferation of cancer cells MG-63 and U2OS, with an IC50 ranging from 0.08 to 0.14 µM. Additionally, Tubulin polymerization-IN-71 induces cell cycle arrest at the G2/M phase and triggers apoptosis in MG-63 cells.
Molekulargewicht:
485.46
Formel:
C25H24FNO8
Target-Kategorie:
Microtubule Associated|||Apoptosis
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