Purinostat, CAS [[1929583-17-4]] Preis auf Anfrage
Artikelnummer:
TGM-T204269
Hersteller Artikelnummer:
T204269
Alternativnummer:
TGM-T204269-10MG,TGM-T204269-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Purinostat is a selective inhibitor of HDACI/IIb with potential anti-leukemic properties. Its mesylate form, Purinostat mesylate, is effective at inhibiting the survival of Ph+ leukemic cells and CD34+ leukemic cells derived from CML patients. Purinostat mesylate targets HDACI/IIb, impacting several crucial factors for leukemia stem cell (LSC) survival, such as c-Myc, beta-Catenin, E2f, Ezh2, Alox5, and mTOR. Additionally, Purinostat mesylate enhances glutamate metabolism in LSCs by increasing GLS1.
Molekulargewicht:
490.518
CAS Nummer:
[1929583-17-4]
Formel:
C23H26N10O3
Target-Kategorie:
HDAC
T204269
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