PPARgamma/delta modulator 2 (Compound 3h) functions as a PPARgamma agonist and a PPARdelta antagonist, with Ki values for PPARgamma and PPARdelta of 2.8 µM and 43 nM, respectively. It significantly enhances adiponectin production and promotes adipogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBM-MSCs). This compound is applicable in research on metabolic diseases related to hypoadiponectinemia.
Molekulargewicht:
564.67
CAS Nummer:
[3116771-70-8]
Formel:
C17H17ClIN5O2Se
Target-Kategorie:
PPAR
T204395
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