sEH inhibitor-19 (Compound (R)-14i) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.2 nM. This compound suppresses the expression of TNF-alpha and IL-6 and exhibits anti-inflammatory effects in mouse models of acute pancreatitis and Carrageenan-induced edema.
Molekulargewicht:
527.535
CAS Nummer:
[3107483-12-2]
Formel:
C28H28F3N3O4
Target-Kategorie:
TNF|||Epoxide Hydrolase|||Interleukin
T204461
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