alpha-Glucosidase-IN-79 (Compound 4d9) is a non-competitive alpha-glucosidase inhibitor with an IC50 of 2.11 µM, demonstrating greater inhibitory potency than the existing alpha-glucosidase inhibitors Acarbose (IC50 of 327.0 µM) and HXH8r (IC50 of 15.32 µM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. alpha-Glucosidase-IN-79 holds promise for research in type 2 diabetes.
Molekulargewicht:
414.475
CAS Nummer:
[3068686-30-3]
Formel:
C21H22N2O5S
Target-Kategorie:
glycosidase
T204466
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