HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 µg/mL and MIC of 4 µg/mL. At a concentration of 100 µM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.
Molekulargewicht:
244.248
CAS Nummer:
[192880-96-9]
Formel:
C7H4N2O4S2
Target-Kategorie:
Virus Protease|||Antibacterial
T204697
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