STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1beta, IL-6, and TNF-alpha, without significant cytotoxicity.
Molekulargewicht:
560.988
CAS Nummer:
[2958649-56-2]
Formel:
C28H25ClN6O5
Target-Kategorie:
NO Synthase|||Interleukin|||STAT|||COX
T204879
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