VEGFR-2-IN-61 (Compound 7b) is an inhibitor of VEGFR-2 with an IC50 of 2.83 µM. It effectively inhibits the proliferation of various cancer cells, including MCF-7 cells, with an IC50 of 2.12 µM. Additionally, VEGFR-2-IN-61 suppresses cell migration and induces oxidative stress and apoptosis in MCF-7 cells.
Molekulargewicht:
435.52
Formel:
C27H25N5O
Target-Kategorie:
Reactive Oxygen Species|||Apoptosis|||VEGFR|||ROS
T204905
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