Dual Galectin-3/EGFR-IN-1 (Compound 29) is a dual inhibitor targeting Galectin-3 and EGFR, with dissociation constants (KD) of 52.29 µM and 3.31 µM, respectively. It inhibits TGF-beta-induced hepatic stellate cell (HSC) activation, induces apoptosis in LX-2 cells, and shows antifibrotic activity in the liver.
Molekulargewicht:
683.709
Formel:
C32H41N7O10
Target-Kategorie:
EGFR|||Apoptosis|||Galectin
T204936
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