CST 530 is a monovalent IAP antagonist. It induces cIAP1 and cIAP2 autodegradation in MM.1S cells (cIAP1 degradation at 0.1 µM and cIAP2 degradation at 1 µM after 16 hours). CST 530 reduces cell viability in multiple cancer cell lines including SUDHL6, MOLM13, and HEL (IC50 values of 170 nM, 420 nM, and 450 nM, respectively).
Molekulargewicht:
560.727
CAS Nummer:
[847137-53-5]
Formel:
C33H44N4O4
Target-Kategorie:
Ligands for E3 Ligase|||Apoptosis|||IAP
T205007
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