W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 µM. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC).
Molekulargewicht:
418.198
CAS Nummer:
[3035498-92-8]
Formel:
C17H12BrN3O5
Target-Kategorie:
ALK|||Apoptosis
T205034
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