Dual Cathepsin L/JAK-IN-1, CAS [[2450279-41-9]] Preis auf Anfrage
Artikelnummer:
TGM-T205041
Hersteller Artikelnummer:
T205041
Alternativnummer:
TGM-T205041-10MG,TGM-T205041-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 µM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-kappaB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).