SARS-CoV-2 Mpro-IN-37 (compound 8r) is an inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 value of 0.0199 µM. It exhibits IC50 values of 0.00945 µM against SARS-CoV-1 Mpro and 0.111 µM against MERS-CoV Mpro. SARS-CoV-2 Mpro-IN-37 demonstrates potent antiviral activity in the nanomolar range without showing cytotoxicity.
Molekulargewicht:
438.582
Formel:
C25H30N2O3S
Target-Kategorie:
SARS-CoV
T205088
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