MAO-B-IN-39 (compound11) is a potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 3.61 µM. It demonstrates strong NRF2 induction capabilities and exhibits significant anti-inflammatory and neuroprotective effects in oxidative stress-related in vitro models. Additionally, MAO-B-IN-39 shows high liver microsomal stability and favorable pharmacokinetic properties in mice, making it a valuable compound for Parkinsons disease research.
Molekulargewicht:
280.3
Formel:
C17H13FN2O
Target-Kategorie:
Nrf2|||Monoamine Oxidase
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