BRD4 Inhibitor-40, CAS [[2994635-04-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: BRD4 Inhibitor-40, CAS [[2994635-04-8]] Preis auf Anfrage
• Artikelnummer: TGM-T205510
• Hersteller Artikelnummer: T205510
• Alternativnummer: TGM-T205510-10MG,TGM-T205510-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.

Produkteigenschaften

• Molekulargewicht: 484.596
• CAS Nummer: [2994635-04-8]
• Formel: C27H32N8O
• Target-Kategorie: Epigenetic Reader Domain|||c-Myc

Bilder

T205510