DBCO-PEG4-VC-PAB-MMAF is a click-reactive Drug-linker that contains a DBCO group and can undergo a strain-promoted acetylene-nitride cycloaddition reaction (SPAAC) with molecules containing an Azide group. MMAF is an effective inhibitor of microtubulin polymerization. DBCO-PEG4-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs).
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