4-(2-Azidoethyl)phenol is a bifunctional small molecule probe featuring both a phenolic hydroxyl group and an azide structure. Its core application lies in the phenol moiety serving as a substrate for APEX2 (ascorbate peroxidase), generating reactive radicals in situ in the presence of H2O2 to label neighboring proteins. Concurrently, the terminal azide group can be linked to alkyne-labeled detection molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) to achieve biotinylation or fluorescence visualization. 4-(2-Azidoethyl)phenol is widely used in proximity labeling-based proteomics research.
Molekulargewicht:
163.18
Reinheit:
98.86%
CAS Nummer:
[74447-34-0]
Formel:
C8H9N3O
Target-Kategorie:
Others
T206147
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