PSF-IN-2 (Compound (C)-30) is a PSF inhibitor with an IC50 value of 0.005 pM. It exhibits anticancer properties, inhibiting the proliferation of 22Rv1 cells with an IC50 value of 0.5 µM. PSF-IN-2 activates the p53 signaling pathway by disrupting PSF-RNA binding, inducing expression of related genes, promoting apoptosis, and inhibiting the cell cycle. This compound is applicable in cancer research.
Molekulargewicht:
312.317
CAS Nummer:
[185418-37-5]
Formel:
C18H16O5
Target-Kategorie:
Apoptosis|||MDM-2/p53
T206152
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