Paeoniflorin-6'-O-benzene sulfonate, CAS [[1390658-79-3]] Preis auf Anfrage
Artikelnummer:
TGM-T206189
Hersteller Artikelnummer:
T206189
Alternativnummer:
TGM-T206189-10MG,TGM-T206189-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
CP-25
Paeoniflorin-6'-O-benzene sulfonate (CP-25) acts as an inhibitor of G protein-coupled receptor kinase 2 (GRK2), preventing its translocation to the cell membrane and inhibiting the JAK1/STAT3 signaling pathway. It suppresses HaCaT cell proliferation induced by IL-17A/CXCL2. In mouse models, CP-25 reduces the levels of inflammatory cytokines and chemokines such as IL-17A, IL-17F, IFN-gamma, TNF-alpha, IL-22, IL-23, CXCL2, CXCL3, and CXCL9, thereby alleviating psoriasis induced by Imiquimod.
