SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimers disease, and multiple sclerosis.
Molekulargewicht:
387.824
CAS Nummer:
[2133010-38-3]
Formel:
C19H21ClF3NO2
Target-Kategorie:
P2X Receptor|||Interleukin
T206318
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