DA-1241 is a GPR119 agonist. By activating GPR119, it downregulates NFkappaB signaling, thereby inhibiting macrophage differentiation. Whether used alone or in combination with DPP4 inhibitors, DA-1241 can alleviate liver inflammation and restore the expression of liver genes linked to inflammation. It is applicable in the research of metabolic dysfunction-associated steatohepatitis (MASH).
Molekulargewicht:
471.543
CAS Nummer:
[1914136-10-9]
Formel:
C25H31F2N5O2
Target-Kategorie:
GPCR
T206401
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