BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 µM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Abeta) peptides and is applicable in Alzheimers disease research.
