HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 µM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.
Molekulargewicht:
374.428
CAS Nummer:
[2920698-73-1]
Formel:
C20H24F2N4O
Target-Kategorie:
AAK1|||AAK1 (AP2 associated kinase 1)
T206896
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