NMDAR antagonist 5, CAS [[3038464-68-2]] Preis auf Anfrage
Artikelnummer:
TGM-T206943
Hersteller Artikelnummer:
T206943
Alternativnummer:
TGM-T206943-10MG,TGM-T206943-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 µM) and effective activity on monoamine transporters (SERT IC50= 1.1 µM, DAT IC50= 0.7 µM, NET IC50= 2.7 µM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 µM, cardiac toxicity IC50= 24.5 µM). It has antidepressant properties and is useful for depression research.
