SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%). It effectively kills the vegetative cells of C. difficile with a MIC of 0.06-0.50 µg/mL and inhibits spore germination in vitro. SCUT1-2 alleviates weight loss and diarrhea symptoms caused by C. difficile infection (CDI) in mice and prevents recurrence.
Molekulargewicht:
545.711
CAS Nummer:
[2930140-57-9]
Formel:
C30H47N3O6
Target-Kategorie:
Antibacterial
T206967
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