CB039 is a selective degrader targeting RBM39 (RNA binding motif protein 39). It facilitates the formation of a ternary complex between RBM39 and the E3 ubiquitin ligase CUL4-DCAF15, resulting in the proteasomal degradation of RBM39. CB039 holds promise for research into cancers dependent on RBM39, such as acute myeloid leukemia (AML) and ovarian cancer.
Molekulargewicht:
481.524
CAS Nummer:
[3056259-55-0]
Formel:
C23H23N5O5S
Target-Kategorie:
PROTACs|||Molecular Glues
T207024
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