SARS-CoV-2 nsp13-IN-7 (Compound 6r) is an inhibitor of SARS-CoV-2 nsp13, with an IC50 of 0.28 µM. This compound disrupts the helicase function of nsp13 by binding to its 5 RNA site and ATP binding site, and it serves as a lead compound for developing antiviral drugs targeting SARS-CoV-2 nsp13.
Formel:
C24H17ClN4O3S
Target-Kategorie:
SARS-CoV
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