JR5-26B is an orally active apoptosis (apoptosis) inducer. It induces cell death via copper-mediated apoptosis and necroptosis (necroptosis). JR5-26B exhibits antiproliferative activity against MIA PaCa-2, PANC-1, PAN02, SU.86.86, and KPC-2 cells, with IC50 values of 0.6, 4.4, 8.0, 1.1, and 3.4 µM, respectively.
Molekulargewicht:
364.38
CAS Nummer:
[2446965-04-2]
Formel:
C19H17FN6O
Target-Kategorie:
Apoptosis
T207308
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