AZD1134 is an orally active, brain-penetrant, and highly selective 5-HT1B receptor antagonist with IC50 values of 2.9 nM (human) and 0.108 nM (guinea pig). It elevates synaptic serotonin levels in guinea pigs and holds potential for research in mental disorders such as depression and anxiety.
Molekulargewicht:
521.58
CAS Nummer:
[442548-99-4]
Formel:
C28H32FN5O4
Target-Kategorie:
5-HT Receptor
T207317
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