Axl-IN-19 (Compound 68) is a selective inhibitor of AXL, a membrane-bound receptor tyrosine kinase, with an IC50 of 5.3 nM and a cellular KD of 6.8 nM. In rats, Axl-IN-19 demonstrates favorable pharmacokinetic properties, featuring low clearance and moderate bioavailability, and is applicable for cancer research.
Molekulargewicht:
507.63
CAS Nummer:
[2870696-46-9]
Formel:
C31H33N5O2
Target-Kategorie:
TAM Receptor
T207381
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