TPS1-IN-1 (Compound O1) is a potent and broad-spectrum inhibitor of TPS1. It exhibits IC50 values of 14.73 µM for MoTPS1 (Magnaporthe oryzae TPS1) and 59.99 µM for BcTPS1 (Botrytis cinerea TPS1). TPS1-IN-1 exerts its broad-spectrum fungicidal effects by disrupting spore germination, appressorium formation, and turgor pressure accumulation in fungi. With good safety profiles, TPS1-IN-1 has potential as a candidate for novel fungicide development.
Molekulargewicht:
477.5
Formel:
C19H26F3N5O4S
Target-Kategorie:
Antifungal
T207389
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