BS-153 is a novel synthetic oxazolidinone drug that exhibits anti-inflammatory effects by blocking the activation of the NF-kappaB/PKCtheta pathway. It can suppress the expression levels of iNOS, COX-2, and pro-inflammatory cytokines (TNF-alpha, IL-1beta, and IL-6) in LPS-stimulated RAW264.7 cells.
Molekulargewicht:
558.98
CAS Nummer:
[1935692-54-8]
Formel:
C27H26ClF3N6O2
Target-Kategorie:
NF-kappaB
T207422
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