PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage
• Artikelnummer: TGM-T207435
• Hersteller Artikelnummer: T207435
• Alternativnummer: TGM-T207435-10MG,TGM-T207435-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PI3K-IN-58 (Compound 17f) is an inhibitor of PI3Kalpha with an IC50 value of 0.039 µM. It shows significant antiproliferative effects on PC-3, 22RV1, MDA-MB-231, and MDA-MB-453 cell lines with IC50 values of 3.48 µM, 1.06 µM, 2.21 µM, and 0.93 µM, respectively. PI3K-IN-58 induces apoptosis by downregulating the expression of anti-apoptotic proteins Bcl-XL and Bcl-2 while upregulating the expression of the pro-apoptotic protein BAX. This compound is applicable for research in cancer targeting through PI3K pathways.

Produkteigenschaften

• Molekulargewicht: 450.51
• CAS Nummer: [3067572-78-2]
• Formel: C22H22N6O3S
• Target-Kategorie: Bcl-2 Family|||Apoptosis|||PI3K

Bilder

T207435