beta-Glu-PAB(CH2NH2)-Exatecan, CAS [[3025108-11-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: beta-Glu-PAB(CH2NH2)-Exatecan, CAS [[3025108-11-3]] Preis auf Anfrage
• Artikelnummer: TGM-T207686
• Hersteller Artikelnummer: T207686
• Alternativnummer: TGM-T207686-10MG,TGM-T207686-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

beta-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is an inhibitor of topoisomerase I. It binds to the topoisomerase I-DNA complex, preventing the re-ligation of DNA strands, leading to DNA breaks and apoptosis. In the tumor microenvironment, where beta-glucuronidase is highly expressed, beta-Glu-PAB(CH2NH2)-Exatecan is specifically cleaved to release Exatecan, which then exerts its cytotoxic effects. Additionally, beta-Glu-PAB(CH2NH2)-Exatecan serves as an intermediate for the synthesis of Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-beta-Glu-PAB-Exatecan. This compound holds potential for cancer research.

Produkteigenschaften

• Molekulargewicht: 790.74
• CAS Nummer: [3025108-11-3]
• Formel: C39H39FN4O13
• Target-Kategorie: Topoisomerase

Bilder

T207686