TCN 237 hydrochloride, CAS [[1784252-90-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: TCN 237 hydrochloride, CAS [[1784252-90-9]] Preis auf Anfrage
• Artikelnummer: TGM-T207772
• Hersteller Artikelnummer: T207772
• Alternativnummer: TGM-T207772-10MG,TGM-T207772-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

TCN 237 serves as an antagonist of NR2B subunit-containing NMDA receptors, with a Ki value of 0.85 nM. It specifically blocks glutamate and glycine-induced currents in whole-cell patch-clamp assays when using L-M(TK-) cells expressing NR2B subunit-containing NMDA receptors. This is in contrast to its effect on L-M(TK-) cells with NR2A- or NR2D subunit-containing receptors and HEK293 cells with NR2C subunit-containing receptors. Additionally, TCN 237 at 3 mg/kg dosage mitigates carrageenan-induced mechanical hyperalgesia in rats.

Produkteigenschaften

• Molekulargewicht: 412.33
• CAS Nummer: [1784252-90-9]
• Formel: C20H24Cl2FN3O
• Target-Kategorie: Others|||iGluR

Bilder

T207772