ATC-324 is a potent autophagy-targeting chimera (AUTOTAC) degrader of the androgen receptor (AR) with a DC50 of 2.05 µM. It induces autophagic-lysosomal degradation of AR, decreases nuclear AR and AR-V7 activity, and exhibits cytotoxic effects on AR-positive prostate cancer cells, making it useful for prostate cancer research.
Molekulargewicht:
1068.09
CAS Nummer:
[2925060-81-5]
Formel:
C53H55F6N5O10S
Target-Kategorie:
PROTACs|||Androgen Receptor
T207785
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