PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 µM) and its associated virulence factor pyocyanin (IC50=2.7 µM). This compound inhibits the synthesis of bacterial biofilms and is significantly cytotoxic to Pseudomonas aeruginosa. Additionally, PqsR-IN-3 exhibits synergistic effects with various antibiotics, such as Ciprofloxacin and Tobramycin.
Molekulargewicht:
417.46
CAS Nummer:
[3033007-79-0]
Formel:
C23H23N5O3
Target-Kategorie:
Antibacterial
T208288
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