Antibacterialagent 166 is a derivative of Nitishinone, functioning as a selective and orally active inhibitor of Fusobacterium nucleatum with an MIC50 of 1 µg/mL. It effectively reduces the migration capability of MC-38 cells induced by Fusobacterium nucleatum. Antibacterialagent 166 is a promising lead compound for studying colorectal cancer (CRC) due to its anti-F. nucleatum properties.
Formel:
C11H8ClN3O4
Target-Kategorie:
Antibacterial
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