Exatecanintermediate 8 serves as an intermediate in the synthesis of Exatecan. Exatecan (DX-8951) is a commonly used cytotoxin component in ADC (Antibody-Drug Conjugate) preparation, and it functions as an inhibitor of DNA topoisomerase I (IC50=2.2 µM).
Formel:
C30H34FN3O9S
Target-Kategorie:
Topoisomerase|||ADC Cytotoxin
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