AK-HW-90 (compound 2B) is a potent pan-Bcr-Abl inhibitor that shows significant inhibitory activity against Imatinib-resistant mutants. It inhibits the resistant Bcr-AblT315I mutant with an IC50 of 0.65 nM. AK-HW-90 offers potential anti-cancer properties and can be utilized in chronic myeloid leukemia (CML) research.
Formel:
C27H29N5O2S
Target-Kategorie:
Bcr-Abl
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
