Antitumor agent-129 (Compound 68) is a derivative of thiazolidine-4-thione and an inhibitor of osteosarcoma (OS), with an IC50 value of 0.217 µM against OS cell activity. It has a half-life of 73.8 minutes in mouse liver microsomes and exhibits favorable pharmacokinetic properties with an in vivo bioavailability (F) of 115% following intraperitoneal administration. Antitumor agent-129 is a potential candidate for OS research.
Formel:
C20H24N4O6S
Target-Kategorie:
Others
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