QC-182 is a potent p300/CBP PROTAC degrader. It reduces p300 protein levels in SK-HEP-1 cells with a DC50 of 93 nM. QC-182 effectively inhibits cell growth in SK-HEP-1 and JHH7 cell lines, with IC50 values of 0.733 µM and 0.477 µM, respectively. QC-182 is applicable for hepatocellular carcinoma (HCC) research.
Molekulargewicht:
816.85
CAS Nummer:
[3032646-96-8]
Formel:
C44H42F2N8O6
Target-Kategorie:
PROTACs|||Histone Acetyltransferase
T209145
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