Antitumor agent-151 (7k) is a notable HsClpP agonist and a potential candidate for leukemia treatment. This compound significantly boosts the proteolytic activity of HsClpP (EC50= 0.79 µM) and exhibits remarkable in vitro antitumor activity (IC50= 0.038 µM). Additionally, Antitumor agent-151 (7k) induces apoptosis.
Formel:
C22H20FN5O
Target-Kategorie:
Apoptosis
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