PROTACPARP1 degrader-1 (Compound CN0) serves as a PROTAC degrader of PARP1. It activates the cGAS/STING immune pathway, ultimately enhancing T cell-mediated tumor cell killing. PROTACPARP1 degrader-1 inhibits DNA damage repair, leading to the efficient accumulation of cytoplasmic DNA fragments.
Formel:
C32H28N6O5
Target-Kategorie:
PROTACs|||PARP
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
