CAIX/VEGFR-2-IN-2 (compound 5e) is a dual-target inhibitor with potent inhibitory effects on CAIX (KI=3.1 µM) and VEGFR-2 (IC50=32.1 nM). This compound is applicable in research involving pancreatic cancer (PANC1), breast cancer (MCF7), and prostate cancer cells (PC3).