LHQ490 is a selective FGFR2 inhibitor with an IC50 of 5.2 nM. It effectively suppresses the proliferation of BaF3-FGFR2 cells, with an IC50 value of 1.4 nM. Additionally, LHQ490 inhibits the proliferation of FGFR2-driven cancer cells and induces apoptosis in these cells.
Formel:
C30H33FN6O2
Target-Kategorie:
Apoptosis|||FGFR
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