QC-01-175 is a heterobifunctional small molecule specifically designed to induce degradation of aberrant tau protein, and it effectively reduces levels of A152T and P301L mutant tau, protects neurons from tau-mediated cytotoxicity. QC-01-175 significantly improves neuronal survival, thereby providing a valuable chemical biology tool for studying tauopathies and developing targeted protein degradation strategies for neurodegenerative diseases.
Molekulargewicht:
626.66
Reinheit:
0.9895
CAS Nummer:
[2267290-96-8]
Formel:
C33H34N6O7
Target-Kategorie:
Microtubule Associated|||PROTACs
T210413
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