4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine, CAS [[1203565-13-2]]

Produktübersicht

• Artikelname: 4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine, CAS [[1203565-13-2]]
• Artikelnummer: TGM-T210517
• Hersteller Artikelnummer: T210517
• Alternativnummer: TGM-T210517-1MG,TGM-T210517-5MG,TGM-T210517-10MG,TGM-T210517-25MG,TGM-T210517-50MG,TGM-T210517-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine is a brominated pyrrolopyridine-based scaffold designed for advanced medicinal chemistry and kinase inhibitor development. Its 7-azaindole (pyrrolopyridine) core serves as a purine bioisostere capable of occupying ATP-binding pockets across diverse kinases. The bromine substituent at the 5-position offers both electronic tuning and a versatile handle for cross-coupling reactions, enabling rapid SAR exploration. The 2-aminopyrimidine moiety further supports hinge-binding interactions, collectively making 4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine a valuable starting point for generating FGFR-targeted inhibitors and other kinase-directed therapeutics.

Produkteigenschaften

• Molekulargewicht: 290.12
• Reinheit: 98.90%
• CAS Nummer: [1203565-13-2]
• Formel: C11H8BrN5
• Target-Kategorie: Others

Bilder

T210517