Nav1.2-IN-2 (Compound 1) is an effective Nav1.2 inhibitor with an IC50 of 0.18 µM for inactivated Nav1.2. Nav1.2-IN-2 suppresses the amplitude and frequency of spontaneous synchronized calcium oscillations (SCO) and inhibits Veratridine-induced calcium influx (IC50 = 1.89 µM), making it suitable for epilepsy research.
Molekulargewicht:
322.4
Reinheit:
99.97%
CAS Nummer:
[7469-49-0]
Formel:
C17H26N2O4
Target-Kategorie:
Sodium Channel
T210523
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